That is, of course, because 552 of those saves came during Hoffman's 16-year career in San Diego.
One of those most proud of the accomplishment was Trevor's brother and Padres third-base coach, Glenn.
He said he was consistently being updated about the ninth-inning events in Milwaukee during the Padres' contest with the Dodgers but that he had not had a chance to speak with Trevor since leaving him a voicemail on Tuesday night.
"It's been pretty crazy, but exciting," Glenn said. "I'm really proud. To reach it is a personal goal for him, but I thought the way the Milwaukee Brewers team and everybody embraced him, it was like him being [in San Diego] for 16 years. That's just the way Trev is, the way he grows on people. That was special."
The final out of Hoffman's 600th save was shown on the video board at PETCO Park during Tuesday's game, which garnered a standing ovation from fans and players alike.
"I stood up, tipped my hat, clapped the whole time I saw it," said Padres closer Heath Bell, a former teammate of Hoffman. "And a tear came ... well, my eyes got watery. I don't want to say I cried. It was a huge honor just to be a setup guy to Trevor. Great guy. I'm happy for him. He is the best."
Trevor said he learned of the Padres' gesture from Glenn following the Brewers' game and that was touched that the milestone was acknowledged in San Diego.
"They're in the middle of a pennant race. Their focus is: Stay ahead of the Giants," Trevor said. "For them to take the time [to acknowledge the milestone], it was a class move by their organization."
The accomplishment also earned high praise from Padres manager Bud Black, who managed Hoffman during his final two seasons in San Diego.
"What a tremendous feat," Black said. There's nothing I respect more than a player passing the test of time through performance, and Trevor has done that."