Another Colorado native, Josh Bard, is expected to handle the catching duties for Thompson. Bard is from Denver.
Thompson, filling in for Chris Young (foot ailment) in his most recent start on July 19 at PETCO Park, fought his command, but limited the Phillies to three runs on nine hits -- including catcher Chris Coste's first career homer in the fourth -- in six innings.
"Being behind in the count so much, I can't go to my strength," said Thompson, who was 3-2 with a 4.30 ERA in nine starts in Williams' absence. "For what I had, stuff-wise, I'll take it. Not my best, not my worst."
Despite picking up his ninth loss of the season, Jennings lowered his ERA, pitching a masterpiece Tuesday night against the Cardinals. Jennings gave up just four hits, pitching all nine innings, but one happened to be an Albert Pujols solo homer, the only run scored by either team on the night -- and the pitch Pujols hit off the top of the outfield fence was a changeup out of the zone, just where Jennings wanted it.
Jennings is 2-0 with a 1.80 ERA aganst the Padres this season. He is 6-9 in his career with a 3.70 ERA in 21 starts against San Diego.
SD: RHP Mike Thompson (3-2, 4.32 ERA)
Right-handed batters, with a .302 average and seven of the nine homers Thompson has allowed, are causing him more trouble than left-handers, who are batting .239.
COL: RHP Jason Jennings (6-9, 3.70 ERA)
Jennings is 29-20 in his career at Coors Field with a 5.24 ERA in 68 starts.
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Leadoff catalyst Dave Roberts is a career .300 hitter with a homer and four walks in 20 at-bats against Jennings.
Official game notes
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Tuesday: Houston (LHP Andy Pettitte, 9-11, 5.18) at San Diego (RHP Jake Peavy, 5-10, 5.01), 7:05 p.m. PT
Wednesday: Houston (RHP Taylor Bucholz, 6-9, 5.96) at San Diego (RHP Woody Williams, 4-2, 3.69), 7:05 p.m. PT