Stauffer, who missed his last start with a tight right hip flexor, retired 12 of the last 13 hitters he faced. He allowed six hits with four strikeouts and one walk.
"I got out of a routine missing a start and I was a little too quick today, but I was able to slow myself down," Stauffer said. "I was able to settle down and find my mechanics."
2010 Spring Training - null
Sights & Sounds
Spring Training Info
Cincinnati pitcher Homer Bailey allowed four runs on nine hits in five-plus innings. He had four strikeouts and one walk.
Reds reliever Dontrelle Willis struggled, allowing five runs on three hits and three walks in one-third of an inning.
Juan Francisco, trying to land a job on the Reds' roster as a reserve infielder, hit a two-run home run, a towering shot to right field in the second inning off Stauffer. Francisco has 10 RBIs this spring for the Reds (14-11-1).
Devin Mesoraco slugged a two-run homer in the seventh as the Reds scored five runs on four hits off Padres reliever Luke Gregerson, who had not allowed a run in his first six spring innings.
Venable, the Padres' leadoff hitter, hit an inside-the-park home run in the first inning. He later added a two-run triple in a six-run sixth inning.
Kevin Frandsen, trying to make the Padres as a utility infielder, had two hits and drove in a run with an opposite-field single in the fourth inning.
Chris Denorfia had two hits for the Padres (11-13-1), raising his spring average to .422.
Reds up next: The Reds are back at Goodyear Ballpark on Thursday against a split squad of Rangers at 4:05 p.m. ET with left-hander Travis Wood going against right-hander Tommy Hunter for Texas. The game will be broadcast on MLB.TV. Including that tilt, the Reds have six Cactus League games remaining, three of them at home. They break camp after the game in Goodyear on Tuesday against the Indians, who share the complex.
Padres up next: The Padres head to Surprise on Thursday for their final night game of the spring at 6:05 p.m. PT against the Rangers. Aaron Harang, who projects as the No. 4 starter, gets the start. Look for newcomer Pat Neshek to get one inning. Neshek was claimed off waivers on Sunday from the Twins and tossed one scoreless inning Tuesday against the Brewers, striking out two. The Padres want to take a good look at the right-hander before breaking camp on Tuesday. Neshek has one Minor League option left, though he could well make the 25-man Opening Day roster.