Peavy, who leads the National League in strikeouts (206) and the Major Leagues in ERA (2.10), pitched seven shutout innings on Saturday against the Dodgers. He needed 99 pitches to get through those seven innings.
Now the Padres are considering having him pitch on three days' rest for the first time this season instead of having him pitch the opening game of a three-game series in Colorado on Friday.
Peavy said that he's amendable to starting on three days rest.
"I feel fine, there's no health problems at this point," Peavy said after the Padres defeated Arizona on Monday, 10-2. "I would have no problem coming back."
Peavy certainly has a good track record against the Diamondbacks this season, going 3-0 in four starts with a 1.71 ERA. Peavy has also fared well at Chase Field against Arizona, as evidenced by his 16-strikeout game here in April.
The Padres probably wouldn't consider having the right-hander pitch on short rest as an option if Peavy wouldn't get an extra day should he start on Wednesday.
San Diego has an off-day on Thursday and then another one Monday before beginning a three-game series against the Dodgers on Tuesday. If Peavy starts Wednesday he won't pitch again until Tuesday, giving him five days rest.
"This could be a situation where you do it," Padres manager Bud Black said. "We'll talk again [Monday]. It's a health thing more than anything. We want to make sure he feels rested and good. I think a lot of factors have to be right."
Peavy hasn't lost since July 22. He has seven victories and one no-decision during that stretch. He's 8-0 this season on the road with a 1.22 ERA.
Should the Padres decide not to start Peavy on Wednesday, they could go with Cassel, who pitched well in his first Major League start against Los Angeles in a no-decision on Friday, allowing three runs in 5 2/3 innings.
Body of work: While pitcher Justin Germano didn't begin the season in the Padres' starting rotation, it's certainly safe to say that he will end the season there.
The rookie right-hander allowed one run over six innings on Sunday in a 5-0 loss to the Dodgers, though he didn't factor in the final decision. Still, the start marked Germano's 12th quality start of the season in 21 overall starts.
Not bad for a guy who didn't make his first start until May 8, and only after pitcher Clay Hensley went on the disabled list with a groin injury.
"I'm very happy about it," said Germano, who is 7-8 with a 4.11 ERA. "It has been a great learning experience and a great opportunity to come up here and get more than my feet wet."
Germano certainly feels like a much different pitcher than the one who made his Major League debut as a 21-year-old in 2004 and even different from the one who started his first game this season in May.
"It's been more approach and situational," he said. "It's learning how to look at what the batter is looking for in certain counts, when to throw my pitches and how to get out of jams.
"My mental strength has increased a lot. I'm not intimidated. I just go out there and pitch my game."
Changing history: Don't think Padres pitcher Greg Maddux wasn't buoyed by the five runs San Diego scored over the first three innings on Monday.
Given his history against Arizona, Maddux -- the future Hall of Famer with 343 career victories entering Monday's contest -- can use all the help he can get.
Maddux went into Monday's start with a 1-10 career record against the Diamondbacks. According to Elias Sports Bureau, that's the lowest winning percentage of any active pitcher against a particular opponent.
Maddux is also 0-6 for his career in games at Chase Field.
"I don't think he's pitched poorly every single game here," Black said. "I think there's games where he's pitched well and didn't win. I don't think it's any one reason ... the ballpark, the enclosure. It's not one thing."
Friar notes: Pitcher Clay Hensley will join the Padres on Tuesday before their game against the Diamondbacks. If catcher Pete LaForest clears waivers, then he will also join the team. Black said there likely won't be any more reinforcements from the Minor League system thereafter. ... Third baseman Chase Headley, the Texas League Offensive Player of the Year, won't be joining the team. Towers would like to see him work on his overall strength in the off-season.
On deck: The Padres continue their three-game series against the Diamondbacks at 6:40 p.m. PT on Tuesday as Chris Young (9-5, 2.38 ERA) gets the start for San Diego. Arizona will go with Doug Davis (12-11, 4.09).