Manager Bud Black mentioned Andrew Cashner, Dale Thayer and Luke Gregerson as candidates to close while Street is out.
Cashner has been a starter and reliever in his career, but he has never closed games in the Majors or Minors. However, he closed during his year at Texas Christian University. He is 2-1 with a 2.08 ERA in 13 innings for the Padres.
"Closing is always fun," Cashner said. "You get the ball with the game on the line at the end of the game and try to get the last three outs of the game."
Thayer accumulated 173 saves in the Minors and one save with the Rays in 2009. He has a 0.00 ERA in four innings with the Padres.
"It's always exciting," Thayer said of closing. "I haven't done it up here, so it's probably more pressure and it'd be more exciting to do it. It's always fun closing games out."
Gregerson closed games at Saint Xavier University, and he earned 48 saves in the Minors and three saves with the Padres from 2009-10. He has a 3.00 ERA in 12 innings with the Friars.
"As similar as the setup and closer role are, you do have that little extra adrenaline, a little extra something to get the job done, because it is the last inning," Gregerson said. "You have to finish it off."