Maybin wasn't in the starting lineup for the third consecutive game on Friday due to a nagging right wrist that has bothered him the last two months.
"You might not see him swing a bat for a few days," said Padres manager Bud Black. "He's a little better [Friday], but it will probably be a couple of days until you see him."
That will leave the Padres a little short-handed for their series against the Rockies, who will start three left-handed pitchers.
Alexi Amarista started in center field for the second time in as many days in Friday's series opener.
This isn't the first time Maybin has dealt with a sore wrist. He missed four games in late May due to similar soreness. He had an MRI at that time that didn't reveal and structural damage.
"There's some action in there," Black said earlier this week.
Black went on to say that a stint on the disabled list for Maybin is "highly unlikely."