The Padres are 26-9 all-time at PNC Park and have never lost consecutive games there.
Last year the Padres came to Pittsburgh and scored 35 runs over a three-game series.
"I'm not sure why," manager Bud Black said. "[Is it] whether we just happened to be playing well when we came here? I just know the last couple of years, we've had some success in this park. It just might have been coincidental [that] the guys were swinging the bats well. I wish I had the answer. I do know in talking to our players, it's a good hitting background, guys see the ball here, they like this park and they feel good about it."