Volquez and Robbie Erlin each worked two scoreless innings before Brewers left fielder Ryan Braun put Milwaukee on the board with a sacrifice fly in the fifth inning. Padres reliever Brandon Kloess faced a bases-loaded, no-out jam in that inning but escaped having allowed only the one run.
"The temperature was kind of hard for a pitcher to get loose," Volquez said. "After the first guy I faced, my arm loosened up a little bit. I was just making pitches. I threw a lot of fastballs. That's my goal right now, to control my fastball. I'm going to throw a lot more fastballs during this Spring Training."
Mark Kotsay and Kyle Blanks had two hits apiece for the Padres, and Blanks drove in a run. Eddy Rodriguez belted a three-run homer in the ninth.
Burgos, pitching for Puerto Rico in the upcoming World Baseball Classic, allowed one hit through two scoreless innings before Blanks singled leading off the third. Three batters later, with two outs, Gyorko hit a low fastball over the center-field fence for a 2-0 Padres lead.
"Actually, it was pretty good," Burgos said. "I pounded the strike zone, I was working with all my pitches. Today, I felt like everything was good."
Brewers center fielder Carlos Gomez walked and singled twice to preserve his 1.000 on-base percentage after two games. He also made a leaping catch at the fence in the second inning to rob Nick Hundley of extra bases.
Up next: The Padres will welcome the first true road team to Peoria Sports Complex on Tuesday, when Homer Bailey and the Reds arrive for a noon PT start. Right-hander Anthony Bass will start for San Diego with left-handers Jose De Paula, Joe Thatcher and Arturo Lopez and right-handers Brad Boxberger, Matt Stites and Kevin Quackenbush on the list to work relief.
Adam McCalvy is a reporter for MLB.com. Read his blog, Brew Beat, and follow him on Twitter at @AdamMcCalvy. This story was not subject to the approval of Major League Baseball or its clubs.