| 3/2/15 |
San Diego Padres signed free agent RHP Starlin Cordero to a minor league contract. |
| 3/8/15 |
RHP Jerry Sullivan assigned to San Diego Padres. |
| 3/8/15 |
LHP Brandon Alger assigned to San Diego Padres. |
| 3/10/15 |
RHP James Needy assigned to San Diego Padres. |
| 3/10/15 |
RHP Colin Rea assigned to San Diego Padres. |
| 3/11/15 |
RF Will Ferrell assigned to San Diego Padres. |
| 3/11/15 |
RHP Daniel McCutchen assigned to San Diego Padres. |
| 3/16/15 |
RHP Luis De La Cruz assigned to San Diego Padres. |
| 3/16/15 |
San Diego Padres optioned 2B Taylor Lindsey to El Paso Chihuahuas. |
| 3/16/15 |
San Diego Padres optioned RHP Tayron Guerrero to San Antonio Missions. |
| 3/17/15 |
C Robert Kral assigned to San Diego Padres. |
| 3/17/15 |
RF Nick Torres assigned to San Diego Padres. |
| 3/17/15 |
CF Travis Jankowski assigned to San Diego Padres. |
| 3/17/15 |
CF Auston Bousfield assigned to San Diego Padres. |
| 3/17/15 |
3B Gabriel Quintana assigned to San Diego Padres. |
| 3/17/15 |
OF Mike McCoy assigned to San Diego Padres. |
| 3/17/15 |
OF Mike McCoy assigned to San Diego Padres. |
| 3/17/15 |
RHP Dennis O'Grady assigned to San Diego Padres. |
| 3/17/15 |
RF Franmil Reyes assigned to San Diego Padres. |
| 3/17/15 |
RHP Zack Segovia assigned to San Diego Padres. |
| 3/18/15 |
RHP Parker Frazier assigned to San Diego Padres. |
| 3/18/15 |
RHP Stephen Kohlscheen assigned to San Diego Padres. |
| 3/18/15 |
San Diego Padres optioned RF Alex Dickerson to El Paso Chihuahuas. |
| 3/18/15 |
San Diego Padres optioned LF Rymer Liriano to El Paso Chihuahuas. |
| 3/21/15 |
RHP Michael Dimock assigned to San Diego Padres. |
| 3/22/15 |
2B Casey McElroy assigned to San Diego Padres. |
| 3/22/15 |
San Diego Padres optioned LHP Robbie Erlin to El Paso Chihuahuas. |
| 3/22/15 |
San Diego Padres optioned RHP Casey Kelly to El Paso Chihuahuas. |
| 3/22/15 |
San Diego Padres optioned RHP Leonel Campos to El Paso Chihuahuas. |
| 3/23/15 |
RHP Bryan Verbitsky assigned to San Diego Padres. |
| 3/23/15 |
RHP Matthew Shepherd assigned to San Diego Padres. |
| 3/24/15 |
LHP Chris Nunn assigned to San Diego Padres. |
| 3/25/15 |
SS Jake Lemmerman assigned to San Diego Padres. |
| 3/26/15 |
San Diego Padres placed C Tim Federowicz on the 60-day disabled list. Recovering from March 2015 right knee surgery |
| 3/26/15 |
2B Benji Gonzalez assigned to San Diego Padres. |
| 3/26/15 |
RHP Adam Cimber assigned to San Diego Padres. |
| 3/26/15 |
San Diego Padres claimed RHP Jandel Gustave off waivers from Kansas City Royals. |
| 3/27/15 |
RHP Samuel Holland assigned to San Diego Padres. |
| 3/28/15 |
IF Josh Bell assigned to San Diego Padres. |
| 3/28/15 |
OF Kyle Gaedele assigned to San Diego Padres. |
| 3/28/15 |
RHP Luis Hernandez assigned to San Diego Padres. |
| 3/29/15 |
OF Tyson Gillies assigned to San Diego Padres. |
| 3/29/15 |
OF Alberth Martinez assigned to San Diego Padres. |
| 3/29/15 |
RHP Kyle Lloyd assigned to San Diego Padres. |
| 3/29/15 |
1B Jason Hagerty assigned to San Diego Padres. |
| 3/30/15 |
RHP Eric Yardley assigned to San Diego Padres. |
| 3/30/15 |
San Diego Padres optioned RHP Cory Mazzoni to El Paso Chihuahuas. |
| 3/30/15 |
San Diego Padres traded LHP Alex Torres to New York Mets for RHP Cory Mazzoni and Player To Be Named Later. |
| 3/31/15 |
LHP Payton Baskette assigned to San Diego Padres. |
| 3/31/15 |
C Jeremy Rodriguez assigned to San Diego Padres. |